Which symptom may indicate a significant adverse reaction to antiemetic therapy in older adults?

Dizziness can be a significant adverse reaction to antiemetic therapy, particularly in older adults. This population is often more sensitive to medications due to physiological changes associated with aging, including alterations in pharmacokinetics and pharmacodynamics. Antiemetics can affect the central nervous system and may lead to sedation, balance issues, and hypotension, which can manifest as dizziness.

Dizziness in older adults can also increase the risk of falls, which is a critical safety concern. Therefore, healthcare professionals must monitor elderly patients closely for signs of dizziness when initiating or adjusting antiemetic therapy. Identifying and addressing this symptom promptly can help manage risks and improve the safety and comfort of older adults receiving treatment for nausea and vomiting.