Which over-the-counter medication can be used as a mild antiemetic?

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Meclizine is an over-the-counter medication that is often used to alleviate nausea and vomiting related to motion sickness and vertigo. It belongs to a class of drugs known as antihistamines, which work by blocking the action of histamine at H1 receptors in the brain, particularly those areas involved in the vomiting reflex. This makes meclizine effective for mild antiemetic purposes, helping to reduce sensations that lead to nausea and vomiting.

Dramamine, while also commonly associated with treating motion sickness, contains dimenhydrinate, which is another antihistamine and can similarly be effective as an antiemetic. However, it is not the preferred choice noted in this question.

Loratadine is an antihistamine used primarily for allergic reactions and does not have significant antiemetic properties, thus it is not suitable for this purpose.

Diphenhydramine is indeed an antihistamine that can reduce nausea, but it is more commonly recognized for its sedative effects and use as an allergy medication rather than as a mild antiemetic in comparison to meclizine. While both diphenhydramine and meclizine can be used for nausea, meclizine is more specifically targeted and recommended for

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